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AAFCO is an independent organization that evaluates commercial diet formulas for adherence to current nutritional guidelines and makes recommendations to pet food safety regulators

The recommended daily amount (RDA) varies, depending on age and other factors, but while the recommended dose for an adult is 2.4 mcg (micrograms), B12 vitamin pills are also sold in doses of 5 to 25 mcg, and even 500 mcg to 1,000 mcg or more

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The above ranges are drawn from animal research and compounding guidelines

When that happens, its essentially burning your skin until you clean it off and change it